99% High Quality API CAS 53179-13-8 Pirfenidone Pfd Powder
| Product Name: | pirfenidone, PFD |
| CAS: | 53179-13-8 |
| MF: | C12H11NO |
| Purity: | 99%+ |
| Appearance: | light yellow to white powder |
Pirfenidone (PFD), whose chemical name is 5-methyl-1-phenyl-2-(1H)pyridone, is a new pyridone compoundwith a broad-spectrum anti-fibrotic effect, which can prevent and Reverse fibrosis and scar formation.
Uses: Pirfenidone was discovered in 1974 by S olomonBMargolin of Marnac Co., Ltd. (TX, USA). In Japan, pirfenidone is classified as an orphan drug, and clinical trials have been initiated to study its possibility as a new drug for the treatment of IPF.
In 2008, pirfenidone was approved for the treatment of IPF in Japan. In February 2008, the European Medicines Agency recommended that EU countries allow pirfenidone to be marketed. Currently, pirfenidone has not been approved by the US FDA for the treatment of IPF. Earlier this month, although the expert panel voted 9:3 to approve the listing of pirfenidone, the FDA still stated that more test evidence is needed to officially approve pirfenidone.
The listing of pirfenidone will bring new hope to patients with pulmonary fibrosis, and it will also make a fundamental change in the clinically incurable situation of this disease. According to the latest clinical research results of pirfenidone capsules published in the 2014 annual meeting of the American Thoracic Society and the New England Journal of Medicine, combining the clinical results of more than 1,000 patients in two phase three clinical trials, taking pirfenidone capsules for 12 months Later, it can prolong the progression-free survival period, delay the decline of FVC (the main indicator of lung function), and reduce the risk of death.
Packing
· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.
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